Florian Mueller

Interim Head Photonic BioImaging (PBI) Platform

Paris, Ile-de-France
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Summary

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Senior
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Top School
Florian Mueller is an interdisciplinary imaging scientist and leader with nine years of professional experience, currently heading the Photonic BioImaging platform and leading the Quantitative RNA Imaging group at Institut Pasteur in Paris. Trained in computational physics (MSc) and biophysics (PhD) in Graz, he combines hands-on microscopy, wet lab work, quantitative image analysis and mathematical modeling to develop single-molecule RNA detection methods with high spatial and temporal precision. His work spans validating biophysical assays (e.g., FRAP/FCS) to building analytical frameworks for FISH and MS2 data, applied across projects from transcriptional regulation to genome organization. He has a track record of securing funding, supervising PhD students, and translating methodological advances into service-oriented platform R&D. Notably, his background in computational physics informs a rigorous, model-driven approach to experimental design and data interpretation that bridges physics and molecular biology.
code10 years of coding experience
job10 years of employment as a software developer
bookGymnasium Feldkirch
bookPh.D., Biophysics, Ph.D., Biophysics at Technische Universität Graz
bookM.Sc., Computational Physics, M.Sc., Computational Physics at Karl-Franzens-Universität Graz
bookHDR (Habilitation à diriger des recherches), HDR (Habilitation à diriger des recherches) at Université Paris-Saclay
languagesEnglish, German, French
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Github Skills (35)

javascript10
python10
image-processing10
deep-learning10
segmentation10
webassembly10
plugin8
user-friendly8
toolbox7
vtk-js6
hosting6
localization6
progressive6
jupyter-notebook4
data-acquisition4

Programming languages (6)

JavaScriptVueHTMLJupyter NotebookMATLABPython

Github contributions (5)

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fish-quant/autofish

Mar 2023 - Dec 2025

Python code to control automated iterative FISH system
Contributions:3 reviews, 15 PRs, 82 pushes in 2 years 9 months
python
Collection of code to analyze RNA localisation from smFISH images.
Contributions:2 releases, 5 PRs, 64 pushes in 1 year
localization
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