George Spracklin
Senior Bioinformatics Engineer
Boston, Massachusetts, United States
Summary
👤
Senior🎓
Top SchoolGeorge Spracklin is a Senior Bioinformatics Engineer with nine years of experience translating complex genomics and epigenetics research into scalable computational pipelines for both academia and industry. He has driven discovery from bench to cloud—developing novel sequencing methods like Protect-seq, applying machine learning and polymer simulations to chromatin architecture at MIT, and delivering precision genomics workflows at Moderna and now Roche for the SBX platform. His toolkit spans Python, NGS, Hi-C/HiChIP, nanopore base-modification analysis, and cloud-native pipeline deployment, enabling rapid, reproducible analysis for clinical and research genomics. Colleagues describe him as equally comfortable designing wet-lab experiments and automating their analysis, with a habit of turning methodological inventiveness into practical, cost- and time-saving tools. Based in Boston, he combines rigorous PhD training in genetics with a track record of cross-disciplinary collaboration that uncovers unexpected biology in nuclear organization.
10 years of coding experience
8 years of employment as a software developer
Doctor of Philosophy (PhD) Genetics, Doctor of Philosophy (PhD) Genetics at University of Wisconsin-MadisonBachelor of Science (BSc), Bachelor of Science (BSc) at Massachusetts College of Pharmacy and Health Sciences
Github Skills (11)
python-bindings10
nextflow9
pipeline9
bioinformatics9
genomics8
modular8
dataframes6
python6
pandas-dataframe5
pandas5
numpy3
Programming languages (3)
Github contributions (5)
gspracklin/genomics_scripts
Jul 2017 - Apr 2025
Contributions:30 pushes, 3 branches in 7 years 10 months
gspracklin/hmm_bigwigs
Jan 2019 - May 2020
using hmm on bigwigs
Contributions:16 commits, 7 PRs, 20 pushes in 1 year 4 months
hmm
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