Joel Berendzen

Founder at GenerisBio, LLC

Santa Fe, New Mexico, United States
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Summary

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Senior
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Top School
Joel Berendzen is a founder and scientist with over a decade translating theoretical biophysics into practical biotech and drug-discovery tools, currently leading GenerisBio from Santa Fe. He discovered that proton and hydroxide “wires” in crystal waters dominate protein conformational energies and drug binding, a finding that reframes structure-based AI, molecular dynamics, and antibody epitope prediction. Joel’s career spans pioneering kinetic crystallography, structural genomics, metagenomics, and award-winning bioinformatics software development at Los Alamos, blending deep physics training (PhD Biophysics, UIUC) with hands-on computational invention. Pragmatic about translation, he has applied ML and translational informatics in both academic health and commercial settings to move this chemistry-driven insight toward actionable ligand and epitope design.
code10 years of coding experience
job25 years of employment as a software developer
bookBachelor of Science (B.S.), Physics, Bachelor of Science (B.S.), Physics at Harvey Mudd College
bookUniversity of Illinois Urbana-Champaign
languagesEnglish
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Github Skills (128)

dependency-management10
webserver10
mer10
dependency-manager10
phylogenetic-trees10
packaging10
overlay10
structural-biology9
python-packaging9
science9
blast9
python9
scientific-computing9
bioinformatics9
gentoo9

Programming languages (9)

TypeScriptShellC++CJavaScriptJupyter NotebookPythonKotlin

Github contributions (5)

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joelb123/click_loguru

Apr 2020 - Oct 2022

Simple loguru logging to file and stderr for your click application
Contributions:76 commits, 29 PRs, 44 pushes in 2 years 5 months
logginglogurustderrclicommand-line-interface
hydrationdynamics/zeigen

May 2021 - Oct 2022

Show structures of protonated water species in atomic-resolution crystal structures
Contributions:64 PRs, 139 pushes, 31 branches in 1 year 5 months
chemoinformaticsquantum-mechanicscrystalresolutionhigh-energy-physics
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