Paul Gueguen
Bioinformatician Single Cell Analysis And Spatial Transcriptomics
Lausanne, Vaud, Switzerland
Summary
👤
Senior🎓
Top SchoolPaul Gueguen is a bioinformatician specializing in single-cell and spatial transcriptomics with eight years of experience at the intersection of immunology and computational biology. He holds a PhD in T cell tumor-immunology and has translated that expertise into both academia and industry, from mapping half a million tumor-infiltrating lymphocytes to contributing to preclinical CAR-T development. At ETH Zürich he delivers reproducible, scalable analyses and advises researchers on experimental design while teaching RNA-seq and mentoring students. Proficient in multi-omics integration, scRNA/scTCR workflows and spatial platforms (Xenium/VisiumHD), he combines strong R-based pipeline development with FAIR, well-documented outputs. Known for making large reference resources openly available, he blends curiosity—summed up in his GitHub tagline "Trying to understand cells"—with a pragmatic focus on actionable biological insights.
8 years of coding experience
1 year of employment as a software developer
Bachelor of Science - BS Cellular biology and physiology, Bachelor of Science - BS Cellular biology and physiology at Université de Bretagne OccidentaleMaster of Science - MS Bioinformatics, Master of Science - MS Bioinformatics at Université de Rennes IDoctor of Philosophy - PhD Immunology / Bioinformatics, Doctor of Philosophy - PhD Immunology / Bioinformatics at Université Paris CitéMaster of Science - MS Bioinformatics - Master GENIOMHE (GENomics Informatics and Mathematics for Health and Environment), Master of Science - MS Bioinformatics - Master GENIOMHE (GENomics Informatics and Mathematics for Health and Environment) at Université Paris-Saclay
French, English
Github Skills (19)
single-cell-genomics10
spatial-transcriptomics10
single-cell-analysis10
cran10
next-generation-sequencing9
transcriptomics8
projection8
bioinformatics7
atlas7
genomics7
shell5
profiling5
r-package5
differential-expression4
gpu3
Programming languages (5)
Github contributions (5)
p-gueguen/Spatial_transcriptomics_tools
Oct 2024 - Jul 2026
List of Spatial Transcriptomics related Tools organized per category
Contributions:1 review, 1 PR, 36 pushes in 1 year 9 months
spatial-transcriptomicspathologysingle-cell-analysis
carmonalab/scGate_models
Jul 2022 - Dec 2022
Cell type gating models for scGate
Contributions:1 release, 79 commits, 57 pushes in 4 months
scgate
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