Paul Sample
Principal Scientist at Outpace Bio
Seattle, Washington, United States
Summary
👤
Senior🎓
Top SchoolPaul Sample is a Principal Scientist based in Seattle with a decade of experience building production agentic AI systems, including autonomous research agents and multi-agent frameworks applied to computational biology. He combines deep domain knowledge from a PhD in Microbial and Eukaryotic Genetics with hands-on bioinformatics and scientific programming experience across startups and industry, from postdoctoral research at the University of Washington to senior roles at Guardant Health and Outpace Bio. Paul has progressed from scientific programmer to principal scientist, shipping production-grade AI and bioinformatics solutions that bridge research and operational workflows. He is drawn to interdisciplinary problems and often applies agentic automation to accelerate biological discovery and analysis. A detail not obvious from titles: his career threads academic rigor with product-focused engineering, enabling rapid translation of complex computational biology ideas into usable systems.
11 years of coding experience
10 years of employment as a software developer
Doctor of Philosophy - PhD Microbial and Eukaryotic Genetics, Doctor of Philosophy - PhD Microbial and Eukaryotic Genetics at The Ohio State University
Stackoverflow
11reputation
6kreached
0answers
2questions
Github Skills (69)
protein-sequences9
prediction9
ssm9
agent-framework8
computational-biology8
python8
splice8
modeling8
genome-analysis8
gateway8
nvidia8
harness7
azure7
rust7
translation7
Programming languages (7)
Github contributions (5)
pjsample/human_5utr_modeling
Apr 2018 - Jul 2019
Modeling of human 5′ UTRs enables the design of new sequences for target levels of translation and 5′ UTR variant prediction.
Contributions:8 commits, 1 PR, 7 pushes in 1 year 2 months
pytorchrnaseqpredictiontranslationutr
pjsample/TCR-Epitope_Modeling
Mar 2019 - Mar 2019
Contributions:19 commits, 16 pushes, 1 branch in 3 days
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