Sam Hesson
Engineering Manager (Agentic Systems) at Meta
Seattle, Washington, United States
Summary
👤
Senior🎓
Top SchoolSam Hesson is an engineering leader and founder with 13 years of experience building AI-driven scientific tools, currently managing Meta’s Agentic Systems incubation team while advising and co-leading Nanome’s push into XR and molecular design. He invented and scaled multi-agent platforms for chemistry and bioinformatics—solving tool orchestration, observability, and enterprise-grade security challenges to enable scientists to chat with agents, run simulations, and collaborate in spatial computing. As Nanome’s CTO he shipped NanomeAI and MARA, a real-time, multi-agent scientific informatics platform used by hundreds of institutions across pharma, materials, and other industries. Sam blends deep product and engineering management with hands-on systems design, and his background includes GE’s software leadership program and founding a university VR club that seeded XR talent—an early signal of his knack for translating emerging interfaces into practical research workflows.
13 years of coding experience
14 years of employment as a software developer
University of California, San DiegoSierra CollegeClayton Valley Charter High SchoolUC CAI CA BRAID NSF I-CORPS Entrepreneurship Center at UCSF, UC CAI CA BRAID NSF I-CORPS Entrepreneurship Center at UCSF at University of California, San Francisco
Github Skills (63)
calculator10
chatgpt10
python10
mathematics10
virtual-reality10
plugin10
ai10
anthropic10
langchain9
llm9
typescript9
computational-chemistry9
blockchain9
ethereum9
generative-ai9
Programming languages (7)
Github contributions (5)
matryx/MatryxDocs
Apr 2018 - Feb 2019
Contributions:10 pushes in 10 months
tyfiero/vetmyhomes
May 2025 - May 2025
Contributions:2 PRs, 13 pushes, 2 branches in 1 day
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