Steven Lewis
Computational Data Manager
Chapel Hill, North Carolina, United States
Summary
👤
Senior🎓
Top SchoolSteven Lewis is a Computational Data Manager with 11 years of experience translating deep biophysics expertise into production-ready computational tools for protein design and immunogenicity prediction. Based in Chapel Hill, he has driven Cyrus Biotechnology’s shift from physics-based modeling to AI-first deimmunization workflows, architecting ML pipelines that normalized 10,000+ yeast-display measurements into robust training datasets. He adapts and extends open-source protein language models (e.g., ThermoMPNN) on proprietary data to predict peptide–MHCII liabilities, pairing domain knowledge with pragmatic software engineering. Previously he stabilized and productionized the massive Rosetta codebase, built cloud microservice backends, and designed API features that let customers embed protein design into their stacks. Known for turning vague scientific requests into deliverable specifications, he instituted feasibility protocols that ensured 100% delivery on approved projects within budget bounds. A PhD-trained biophysicist who codes fluently in C++ and Python, he thrives at the intersection of wet-lab insight and scalable ML systems.
11 years of coding experience
7 years of employment as a software developer
HS, HS at Maggie L Walker Governor's School for Government and International StudiesDoctor of Philosophy (PhD) Biochemistry Biophysics and Molecular Biology, Doctor of Philosophy (PhD) Biochemistry Biophysics and Molecular Biology at The University of North Carolina at Chapel HillBachelor of Science (BS) Chemistry Biology, Bachelor of Science (BS) Chemistry Biology at William & Mary
Github Skills (24)
keyboard9
validation9
karabiner9
bioinformatics9
genomics9
macos8
data-analysis8
python8
pandas8
data-structure8
data-science8
prediction-model7
pdb-files7
data-structures7
packing5
Programming languages (7)
Github contributions (5)
rlabduke/Protocol-Captures
Feb 2015 - May 2016
Contributions:13 commits, 10 pushes in 1 year 2 months
CyrusBiotechnology/ThermoMPNN-docker
Oct 2024 - May 2025
This repo contains the Dockerfile and the drone hookup for ThermoMPNN.
Contributions:26 pushes, 4 branches in 7 months
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