Yunguan Wang
Assistant Professor at Cincinnati Children's Hospital Medical Center
Ohio, United States
Summary
👤
Senior🎓
Top SchoolYunguan Wang is an assistant professor and bioinformatics scientist with nine years of experience applying machine learning, multi-omics integration, and big-data mining to translational problems in drug discovery and spatial single-cell biology. He has built deep learning and latent-graph models for image and spatial transcriptomics denoising, designed large analysis pipelines that uncovered drivers in prostate cancer, translocation RCC, and SARS-CoV-2 immune responses, and led computational screens that prioritized small molecules for cystic fibrosis. His work bridges algorithm development and wet-lab validation—screening over a million L1000 profiles to nominate compounds that restored CFTR function—demonstrating an uncommon end-to-end competence from model to experiment. Based in Ohio, he combines PhD-level bioinformatics training with practical data science roles at leading institutions (Harvard, UT Southwestern, Cincinnati Children’s), consistently translating high-dimensional data into testable biological hypotheses.
10 years of coding experience
9 years of employment as a software developer
Doctor of Philosophy - PhD, Bioinformatics, Doctor of Philosophy - PhD, Bioinformatics at University of Cincinnati College of MedicineB.E., Bioengineering, B.E., Bioengineering at Dalian University of Technology
English, Chinese
Stackoverflow
23reputation
710reached
0answers
1question
Github Skills (39)
profiling9
go6
anaconda6
unicode6
punctuation6
ide6
algorithm6
cjk6
differential-expression5
bioinformatics5
mutation5
source-engine5
language-server-protocol5
python5
qt5
Programming languages (9)
Github contributions (5)
yunguan-wang/Tissue_positioning_system
Sep 2020 - Oct 2022
A quantitative, unsupervised algorithm for hapatocytes zonal expression analysis
Contributions:1 release, 24 commits, 46 PRs in 2 years
yunguan-wang/SPROD
Mar 2021 - Dec 2022
SPROD: Spatial expression profiling de-noising
Contributions:1 release, 178 commits, 21 PRs in 1 year 9 months
profiling
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